Rita Borsellino (2 June 1945 – 15 August 2018) was an Italian Sicilian anti-Mafia activist and politician. She was a Member of the European Parliament (MEP) for the Democratic Party. She was on the European Parliament from 2009 to 2014. Borsellino was born in Palermo, Italy.
On 4 March 2012 she ran in a centre-left open primary for the seat of Mayor of Palermo, but was defeated by independent candidate Fabrizio Ferrandelli.
Borsellino died in Palermo on 15 August 2018 from pancreatic cancer at the age of 73.