Wyrzysk (former German Wirsitz) is a town in Poland with 5,263 (2004) inhabitants. It is in Piła County, Greater Poland Voivodeship.
Commune Wyrzysk has a population of about 14,500 and an area of 160.7 km2 (62.0 sq mi). It is on the northern edge of Greater Poland Voivodeship. On the east border is commune Sądki in the Kuyavian-Pomeranian Voivodeship.