Maria de Lourdes Ruivo da Silva de Matos Pintasilgo, GCC GCIH GCL (Portuguese pronunciation: [mɐˈɾiɐ dɨ ˈluɾdɨʃ pĩtɐˈsiɫɡu]); (Abrantes, São João Baptista, 18 January 1930 – Lisbon, 10 July 2004) was a Portuguese chemical engineer and politician. She was the first and to date only woman to serve as Prime Minister of Portugal, and the second woman to serve as Prime Minister in Western Europe, after Margaret Thatcher.
Maria de Lourdes Pintasilgo died of cardiac arrest at her home in Lisbon on 10 July 2004, aged 74.