James Hutchinson Woodworth (December 4, 1804 – March 26, 1869) was an American politician. He was in the Illinois State Senate and in the Illinois State House of Representatives. He was a Chicago Alderman. He was elected to consecutive terms as Mayor of Chicago, Illinois (1848–1850) as an Independent Democrat. He was in the US House of Representatives for one term as a member of the Republican Party.
Woodworth was born on December 4, 1804 in Greenwhich, New York. He was married to Almrya Booth from 1842 until his death in 1869. They had two children. Woodoworth died on March 26, 1869 in Chicago, Illinois from an illness, aged 64.