Jefferson City is the capital of the U.S. state of Missouri. It is also county seat of Cole County. (The Jefferson City metropolitan area includes all of Callaway and Cole counties.) As of the 2010 census, the population was 43,079. Jefferson City was named after Thomas Jefferson, the third president of the United States.
Jefferson City is on the northern edge of the Ozark Plateau on the southern side of the Missouri River near the geographic center of the state, in a region known as Mid-Missouri. It is at the western edge of the Missouri Rhineland, one of the major wine-producing regions of the Midwest.