Alpine is a city in the state of Texas in the United States. It is the county seat of Brewster County. About 6,054 people lived there in 2013.

Alpine was first named Osborn for the part of the railroad that it was near. From 1883 to 1888, Alpine was named Murphyville, for the owners of the land where the spring was that the railroad used to get water for its steam locomotives.

Sul Ross State University opened in Alpine in Summer of 1920. Big Bend National Park was started near Alpine on June 12, 1944. Both of these things forced people to move to Alpine.