What is a SNP?

Q: What is a SNP?


A: A single nucleotide polymorphism is a DNA sequence variation in a population, characterized by a single nucleotide difference in the genome.

Q: What does SNP stand for?


A: SNP stands for single nucleotide polymorphism.

Q: How many alleles do common SNPs have?


A: Most common SNPs have only two alleles.

Q: Where do SNPs occur most often in the DNA?


A: SNPs occur most often in regions of the DNA which do not affect the survival of the organism.

Q: What factors can affect SNP density?


A: Factors like genetic recombination and mutation rate can also affect SNP density.

Q: What are some practical applications of genetic variations between individuals?


A: Genetic variations between individuals (particularly in non-coding parts of the genome) are sometimes exploited in DNA fingerprinting, which is used in forensic science. These genetic variations also cause differences in our susceptibility to disease.

Q: What is an example of a genetic variation linked to a higher risk of a specific disease?


A: For example, a single base mutation in the APOE (apolipoprotein E) gene is associated with a higher risk for Alzheimer's disease.

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