What is a prion disease?

Q: What is a prion disease?


A: A prion disease is a disease caused by prions, which are structurally altered versions of small proteins that are normally expressed in cells.

Q: Are prions able to replicate and transmit diseases?


A: Yes, prions are able to replicate and transmit diseases through physical contact with normal proteins resulting in a structural change from the normal state to the prion state.

Q: How are prions different from mutations of genes resulting in the expression of mutant proteins?


A: Unlike diseases caused by mutations of genes resulting in the expression of mutant proteins, prions are able to replicate and transmit diseases through physical contact with normal proteins.

Q: Are prions considered to be alive?


A: No, prions are not considered to be alive because they do not have their own metabolism, they do not possess genes, and cannot naturally reproduce outside a host cell.

Q: Are prion diseases common?


A: No, prion diseases are very rare.

Q: What are the two common signs seen in typical prion diseases?


A: The two common signs seen in typical prion diseases are neurologic diseases.

Q: Is treatment available for most prion diseases?


A: No, no treatment is available for most prion diseases.

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