Post-traumatic stress disorder (PTSD) is a psychiatric condition that can occur after exposure to a frightening, dangerous, or deeply distressing event. It is commonly classified among anxiety-related and trauma- and stressor-related disorders and may develop after single incidents (for example, assault, accidents, or disasters) or repeated exposure to trauma. For general context on its diagnostic grouping see anxiety and related disorders, and for examples of events that commonly precipitate PTSD see severe harm or traumatic experiences.

Core symptoms and clinical features

PTSD typically involves several characteristic symptom clusters that persist beyond the initial aftermath of the event. Clinicians and researchers often describe four core groups: intrusive re-experiencing (flashbacks, distressing memories, nightmares), avoidance of reminders (efforts to avoid thoughts, places, or people associated with the trauma), negative alterations in thoughts and mood (persistent negative beliefs, emotional numbness), and hyperarousal or hypervigilance (sleep problems, exaggerated startle, irritability). Symptoms vary in intensity and may fluctuate over time; for some people acute stress reactions resolve, while for others the disturbance becomes chronic and disabling.

Causes, risk factors, and biological considerations

PTSD arises from a combination of the traumatic event itself and individual vulnerability factors. Higher risk is associated with severity and proximity of the trauma, repeated or long-term exposure (for example in some emergency responders or victims of ongoing abuse), prior traumatic experiences, a history of anxiety or mood disorders, and limited social support. Biological research points to alterations in stress-response systems and brain circuits involved in memory and fear regulation, though no single biomarker defines the disorder.

History and terminology

The cluster of symptoms now labeled PTSD has been observed across cultures and historical periods. In military contexts it was once called shell shock or combat-related syndromes. Conditions with overlapping features have also been termed traumatic war neurosis or post-traumatic stress syndrome. Historical descriptions of trauma responses appear in accounts such as those of civilians who witnessed catastrophic events: for example, observers of the Great Fire of London later recorded persistent fear and sleep disruption in their diaries, an early descriptive example often cited in histories of trauma (Great Fire of London, contemporary diary accounts).

Diagnosis and distinctions

Diagnosis is clinical and based on standardized criteria in systems such as the DSM and ICD. Important distinctions include differentiating PTSD from shorter-lived traumatic stress reactions, which may resolve without long-term impairment, and from immediate wartime responses like combat stress reaction, which historically has been treated as an acute condition. A formal diagnosis generally requires that symptoms persist for a specified duration and cause marked distress or functional impairment.

Treatment and prognosis

Effective care is available and commonly includes trauma-focused psychotherapies—cognitive-behavioral approaches such as prolonged exposure and cognitive processing therapy, and eye movement desensitization and reprocessing (EMDR)—alongside supportive interventions. Medications, particularly certain antidepressants, can help reduce symptoms for some patients. Early intervention, strong social supports, and tailored treatment plans improve the chance of recovery, though some people experience long-term difficulties and may need ongoing care.

Impact, comorbidity, and public health importance

PTSD can impair relationships, work, and daily functioning and often co-occurs with depression, substance misuse, chronic pain, and other anxiety disorders. Because traumatic events are common in many populations—conflict survivors, emergency workers, survivors of assault or accidents—the disorder has substantial personal and societal consequences and is a focus of research and public health efforts to improve access to effective treatments and prevention strategies.

This article summarizes widely accepted features and approaches to PTSD. For individualized assessment and treatment one should consult qualified health professionals and local clinical guidelines.