What is oestradiol?

Q: What is oestradiol?


A: Oestradiol is an oestrogen, a steroidal hormone mainly secreted by the ovaries and is a main female hormone.

Q: What are the functions of oestradiol in females?


A: Oestradiol regulates female characteristics, the maturation of female sex organs, the oestrus and menstrual cycle, and stimulates the production of mammary glands.

Q: How do the serum concentrations of oestradiol and other female hormones change during the menstrual cycle?


A: The serum concentrations of oestradiol and other female hormones change throughout the menstrual cycle.

Q: What happens to the serum concentrations of oestradiol during gestation?


A: During gestation, there is a high serum concentration of oestradiol E3.

Q: What happens to the serum concentrations of oestrone during menopause?


A: During menopause, oestrone has the higher concentration.

Q: How does oestradiol affect bone formation?


A: Oestradiol has a big effect on bone formation. Women past menopause have an accelerated loss of bone because they have less oestrogen.

Q: Does Oestradiol have any functions in males?


A: Yes, oestradiol also has some functions in males but at a much lower level. Its serum concentration in men is < 35 pg/mL, equivalent to that seen in post-menopausal women.

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