The Ñuble Province (Spanish: Provincia de Ñuble) was one of the provinces of the Chilean region of Bío Bío (VIII). The provincial capital was the city of Chillán.
It was the second province in area in the Bío Bío region, after the Bío Bío province, and the second with more people living in it, after the Concepción province.
The province was created in 1974, as the historical province of Ñuble was supressed by the military dictatorship of Augusto Pinochet. In 2018 the province was converted in the Ñuble Region.