What is non-coding DNA?

Q: What is non-coding DNA?


A: Non-coding DNA are parts of an organism's DNA which do not code for protein sequences.

Q: What is the amount of non-coding DNA in different species?


A: The amount of non-coding DNA varies greatly between species. For example, over 98% of the human genome is noncoding DNA, while only about 2% of a typical bacterial genome is non-coding DNA.

Q: What was initially thought to be the purpose of non-coding DNA?


A: At first, much non-coding DNA had no known biological function and it was called junk DNA, particularly in the press.

Q: Are there any functions associated with some types of non-codingDNA?


A: Yes, many non-coding sequences are functional. These include genes for functional RNA molecules and other sequences such as "start replication" signals, centromeres, and telomeres.

Q: Is it possible that some types of non- codingDNA have yet to be discovered functions?


A: Yes, other noncoding sequences have not yet been discovered functions which can be inferred from the high levels of sequence similarity seen in different species' DNAs.

Q: What did ENCODE project suggest about the percentage of useful/functionalnon codingDNA in humans?


A: The Encyclopedia of DNA Elements (ENCODE) project suggested in September 2012 that over 80%of DNAs in human genome "serves some purpose".

Q: Was this conclusion accepted by all scientists or were there criticisms against this suggestion?


A: This conclusion was strongly criticized by some other scientists.

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