The title of this article is ambiguous. For other meanings, see Neubrandenburg (disambiguation).

Neubrandenburg (Low German Niegenbramborg or shortened Bramborg) is the district capital of the Mecklenburg Lake District in Mecklenburg-Western Pomerania. The third-largest city in the German state, it is one of the four regional centres and the main city in the southeast, with a population of about 65,000 and a catchment area of about 420,000. It is centrally located between the Baltic Sea and the conurbations of Szczecin to the east, Rostock to the northwest, Berlin to the south and Hamburg to the west.

Neubrandenburg is known for Europe's best-preserved brick Gothic city fortifications, its event and cultural landscape including the Concert Church and the Neubrandenburg Philharmonic Orchestra, as a sports city and for the Tollensesee lake near the city centre in the Mecklenburg Lakes holiday region. Around 2011, the city had the second largest economic power per inhabitant of all cities in the new federal states. Important economic sectors are plant and mechanical engineering, high technology, logistics, health care, IT and services. Due to its high centrality, Neubrandenburg also has supraregional significance as a shopping city. The town is the location of several large schools and since 1988 has also been a university town. Because of the distinctive four medieval city gates, Neubrandenburg officially bears the name addition "Four Gates City" since 2019.