Meninges: Layers and Role in Protecting the Central Nervous System

The dura mater (often just called "dura") is the outermost meninges. It consists of two sheets, whereby at least in the area of the skull bone the outer sheet is identical with the periosteum. The two sheets separate from each other at circumscribed points to form so-called "sinuses", a special form of venous blood conduit. The inner leaf of the dura mater draws into the great fissure between the two cerebral hemispheres and into the fissure between the two cerebellar hemispheres, and forms the falx cerebri, the falx cerebelli, and the tentorium cerebelli by juxtaposition with the inner dural leaf of each adjacent part of the brain. The falx cerebri separates the two cerebral hemispheres in the sagittal plane and merges into the falx cerebelli, which separates the two cerebellar hemispheres. Correspondingly, the tentorium cerebelli (tent roof of the cerebellum) forms, separating the cerebrum from the cerebellum. It is a structure lying rather horizontally in the skull, which has a complex three-dimensional shape due to its points of attachment to different parts of the bony skull. The diaphragma sellae forms analogously. The pituitary gland lies underneath and is thus positioned extradurally (outside the dura).

In the area of the spinal cord, the dura mater is not connected to the spinal canal. There are only a few bony attachment points of the dura mater spinalis: on the one hand, the beginning at the edge of the foramen magnum of the occipital bone, on the other hand, the end of the dural tube at the level of the 1st/2nd cruciate vertebra. The filum terminale, which begins as a continuation of the medullary cone (conus medullaris), continues from here as filum terminale externum or durale and ends at the second coccygeal vertebra, where it is also fixed bony and is in continuity with the ligamenta sacrococcygea anteriora.

In the spinal canal there is a space between the dura and the spinal canal, the epidural or peridural space, which is filled with fatty tissue. The exiting nerve roots can be anaesthetised via an injection into this space (peridural anaesthesia).

The dura is very sensitive to pain. In the cranial region, sensory innervation is provided by the ramus tentorii of the ophthalmic nerve and the rami meningei of the anterior ethmoidal nerve, the maxillary nerve, the mandibular nerve and the vagus nerve.

The dura mater is predominantly taut, collagen-fibrous connective tissue and has primarily the function of an organ capsule.

The arachnoid membrane (also called cobweb skin, spider web skin or spider tissue skin) is the middle meninges of the brain. It lies adjacent to the dura mater on the inside and is separated from it by a usually closed, partly fluid-filled capillary area, the subdural fissure (spatium subdurale), which only becomes dilated and recognizable as a subdural space by excessive pathological fluid or air accumulation. This may occur when the bridging veins (venae superiores cerebri), which open into the superior sagittal sinus and thus breach the dura mater overlying the arachnoid, rupture and the escaping blood fills the subdural space. Hemorrhage into the subdural space is called a subdural hematoma (SDH).

The arachnoid, like the dura mater, skips the furrows of the brain and gets its name from the strong whitish patterning with fine fibers of collagenous connective tissue, which gives it a spider-web-like appearance. Button-shaped outpouchings protrude from the arachnoid into the venous blood conduits in the dura mater (sinus durae matris). These projections are called arachnoid villi (pacchioni granulations, granulationes arachnoideae) and are a site of CSF reabsorption.

Below the arachnoid lies the subarachnoid space (spatium subarachnoideum), which is filled with cerebrospinal fluid and thus represents the outer cerebrospinal fluid space. In this space between the arachnoid and the pia mater lie numerous superficial arteries and veins of the brain.