The arrondissement of Oloron-Sainte-Marie is an arrondissement of France. It is part of the Pyrénées-Atlantiques département. Its capital is the city of Oloron-Sainte-Marie.

It is the largest and the southernmost of the arrondissements of the department, with an area of 2,884.9 km2 (1,114 sq mi), and a population of 74,614 inhabitants; its population density is of 25.9 inhabitants/km².