What is the Link reaction?

Author: Leandro Alegsa

Q: What is the Link reaction?



A: The Link reaction, also known as pyruvate decarboxylation, is a reaction that acts as a link between the metabolic pathways of glycolysis and the citric acid or Krebs cycle.

Q: Where does the Link reaction take place in eukaryotes?



A: In eukaryotes, the Link reaction takes place only inside the mitochondrial matrix.

Q: Where does the Link reaction take place in prokaryotes?



A: In prokaryotes, similar reactions take place in the cytoplasm and at the plasma membrane.

Q: What happens to pyruvate during the Link reaction?



A: During the Link reaction, pyruvate is decarboxylated: CO2 is removed.

Q: What is formed when pyruvate is added to CoA during the Link reaction?



A: When pyruvate is added to CoA during the Link reaction, it forms Acetyl CoA.

Q: Why is the Link reaction important?



A: The Link reaction is important as acetyl-CoA is needed for the Krebs cycle to happen.

Q: What is Acetyl CoA used for?



A: Acetyl CoA is used in the Krebs cycle to produce energy.


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