Incubation period

The incubation period (from Latin incubatio, "incubation, incubation", from Latin incubare 'to incubate') is a term from infectiology and describes the time that elapses between infection with a pathogen and the appearance of the first symptoms ("outbreak").

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Depending on the disease, the incubation period can range from a few hours to several years (see below). This depends on how quickly and in what specific way the corresponding pathogens multiply in the body (temperance, virulence), how they affect the body, how strong the immune system is and when symptoms can first be noticed. Occasionally, with relatively harmless pathogens, there may even be no symptoms at all despite an infection (so-called inapparent infection).

Many diseases can also be infectious (contagious) even before the onset of symptoms. This is the case, for example, when the pathogen has already been able to multiply sufficiently locally (e.g. in the nasopharynx), but has not yet penetrated the bloodstream, as a result of which the immune system has not yet reacted in a strength that leads to the classic (indirect) symptoms such as fever and aching limbs. For this reason, historically, people arriving from endemic areas were not allowed to enter the country for 40 days (quarantaine in French; hence quarantine) in many places, to make sure that they were not ill.

In the case of poisoning, the phase until the onset of symptoms is called latency, whereas in the case of infection, latency refers to the interval between infection and the onset of infectivity described above.

Incubation periods of some human infectious diseases

  • The poliovirus multiplies in the lymphatic tissue of the digestive tract (enterovirus). After one to two weeks, unspecific symptoms such as fever and aching limbs may occur; this is then the incubation period. About half a week later, the full clinical picture of polio can then follow.
  • In rabies, the duration of the incubation period depends on the localization of the bite with which the virus was transmitted. The longer its path along the peripheral nerves to the brain, the longer the incubation period.
  • Local infections have a correspondingly short incubation period.

The following is a list of known infectious diseases:

Disease

between

and

Time unit

Comment

Adult T-cell leukemia

60

0more

00Years

Cholera

,000,5

,0004,5

00days

COVID-19

01

014 (27)

00days

On average (median) 5 to 6 days

Dengue fever

03

014

00days

Average 4 to 7 days

Diphtheria

01

010

00days

Average 2 to 5 days

Ebola fever

02

021

00days

Most often between 8 and 10 days

Spotted Fever

10

014

00days

Gonorrhoea

02

3–5

00days

Influenza - Flu

01

004

00days

Average 2 days

hepatitis A

14

028

00days

hepatitis B

30

180

00days

Average 75 days

hepatitis C

14

180

00days

Meningitis - meningitis

02

010

00days

Average 4 days

HIV

21

042

00days

Whooping cough - pertussis

06

020

00days

Mostly 9 to 10 days

Polio

03

035

00days

Mostly 7 to 14 days

Leprosy

,000,5

005

00Years

Can also be up to 20 years.

malaria quartana

16

050

00days

tertian malaria

12

018

00days

incubation period may also be several months.

malaria tropica

10

015

00days

Marburg fever

03

009

00days

Measles

8–10

10–12

00days

Cutaneous anthrax

01

007

00days

Pulmonary Anthrax

01

007

00days

Can also be up to 2 months

Intestinal Anthrax

1–3

007

00days

Mumps

12

025

00days

On average 16 to 18 days

Plague - bubonic plague

01

007

00days

Plague - pneumonic plague

01

003

00days

Ringworm

04

014

00days

Rubella

14

021

00days

Relapse Fever

01

014

00days

Often about 5 days

Dysentery - amoebic dysentery

01

007

00days

Dysentery - Bacterial Dysentery

02

007

00days

Salmonella

012

024

00hours

Scarlet fever

02

004

00days

Syphilis

10

090

00days

Average 21 days

Rabies

30

090

00days

Can also be between a week and a year.

Tuberculosis

14

070

00days

Typhoid

07

021

00days

Extreme values between 3 and 60 days

Avian influenza_H5N1, Avian influenza H7N9 (avian flu)

01

05

00days

Chickenpox

10

021

00days

Mostly 14 to 17 days

Tetanus - Tetanus

03

021

00days

Questions and Answers

Q: What is an incubation period?


A: An incubation period is the time it takes between the day a person is infected with a pathogen and the day that the person starts having symptoms of the disease.

Q: Can the length of an incubation period vary between different diseases?


A: Yes, the length of an incubation period can vary between different diseases.

Q: What is an example of a disease with a short incubation period?


A: The common cold is an example of a disease with a short incubation period, usually taking about one to three days to develop symptoms.

Q: Can a person with HIV give other people the virus during the incubation period?


A: Yes, a person with HIV can still give other people the virus during the incubation period, even though they do not yet have symptoms.

Q: What does the pathogen do during the incubation period?


A: The pathogen is making copies of itself during the incubation period.

Q: Does every disease have an incubation period?


A: Not every disease has an incubation period, but many infectious diseases do.

Q: Is it possible for symptoms to appear before the end of the incubation period?


A: It is possible for symptoms to appear before the end of the incubation period, but typically symptoms begin to appear after the incubation period has passed.

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