The earliest preserved anatomical studies are found in the Edwin Smith papyrus, which is dated to the 17th century BC. Among other things, the heart and coronary vessels, liver, spleen and kidneys, hypothalamus, uterus and bladder, and blood vessels are treated.
The Papyrus Ebers from the last quarter of the 16th century BC contains a treatise on the heart, in which the blood vessels are also described.
Nomenclature, methodology and applications go back to the ancient Greek physicians. Descriptions of muscles and the skeleton can be found in the Corpus Hippocraticum (especially On Fractures and On Joints), although in Hippocratic medicine human physiology was more important than anatomy. Aristotle used dissection of animals to describe the anatomy of vertebrates. Praxagoras of Kos already knew the difference between arteries and veins in the 4th century BC.
The beginnings of systematic anatomy arose in ancient Babylon. A first anatomical school existed in Alexandria in the 2nd century BC. The rulers of the Ptolemaic Empire (Ptolemy I and especially Ptolemy II come into consideration) allowed the opening of corpses there for anatomical studies, mostly on executed persons. Herophilos of Chalcedon performed the first scientific autopsies and also vivisections on humans and animals. He is said to have dissected 600 prisoners alive and is considered the "father of anatomy". He rejected Aristotle's view that the heart was the seat of the intellect and instead named the brain. Other anatomists in Alexandria were Erasistratos and Eudemos of Alexandria.
The treatise On the Designation of the Parts of the Human Body, written by Rufus of Ephesus in the 2nd century, is the oldest extant anatomical textbook whose main purpose was to teach anatomical nomenclature. According to Rufus, theoretical instruction was supplemented by illustrations on living persons, with the external body parts being demonstrated on slaves.
In the 2nd century AD, Galenos of Pergamon systematically summarized the medical knowledge of ancient physicians, among other things in a 15-volume anatomical work On the Procedure of Dissection. As a doctor of gladiators, he was able to study various types of wounds and thus also human anatomy in detail. He carried out further studies on pigs and monkeys. His writings formed the basis for the works of the Middle Ages, including Avicenna's Canon of Medicine.
From about 1300 onwards, anatomical doctrinal dissections were occasionally performed, especially in Upper Italy. Such demonstrations, however, served primarily the purpose of confirming the teachings of ancient authors or authorities.
From the 15th century onwards, anatomy experienced a new impetus, inspired by ideas of humanism and the Renaissance. After anatomy had failed to make much progress in the Middle Ages, the Flemish anatomist Andreas Vesalius (1514-1564) corrected assumptions or beliefs that had hardly been questioned for centuries, outraging many of his colleagues. His work made him the founder of modern anatomy. Starting from upper Italian models, anatomical teaching by means of dissecting human cadavers also spread to German-speaking countries in the 16th century. For example, from 1530 at the latest in Germany, from 1535 by Burghard Mithobius (1501-1564) at the University of Marburg.
William Harvey is considered the discoverer of the circulatory system in the West and a pioneer of modern physiology.
Since then, anatomy took a high place in the fine arts, dissections on humans and animals were part of the basic education of students. Artists such as Michelangelo, Raphael, Dürer and Leonardo da Vinci (1452-1519) spent years studying the human body. Da Vinci's Codex Windsor surpassed the work of Vesalius, born 62 years later, in its scientific accuracy. The close collaboration of artists and anatomists produced medical writings of exceptionally high quality, such as the textbook of the Fleming Philip Verheyen (1648-1710).
In the Age of Enlightenment, anatomical theatres were erected which, in addition to their scientific value, had a high visual value.
The first popular photographic atlas of anatomy was published in 1982/83 by Johannes W. Rohen and Chihiro Yokochi.