Francis Cooke (ca. 1583 - April 7, 1663) was a passenger on the Mayflower. He was a signer of the Mayflower Compact and was an important member of Plymouth Colony.
Francis Cooke lived in England and then in Leiden Netherlands.
Cooke married Hester Mahieu at the French Walloon Church in Leiden. In August 1606 Francis Cooke and his wife moved to Norwich in county Norfolk in England. They did not live there long and returned to Netherlands. Their son John was baptized at the Walloon Church in Leiden in 1607.