What is DNA repair?

Q: What is DNA repair?


A: DNA repair is the process by which a cell identifies and corrects damage to its DNA molecules caused by normal metabolic activities and environmental factors, such as UV light and radiation.

Q: How many molecular lesions can occur per cell per day?


A: There are as many as a million molecular lesions per cell per day.

Q: What can structural damage to the DNA molecule cause?


A: Structural damage to the DNA molecule can alter or eliminate the cell's ability to transcribe the affected gene.

Q: What can potentially harmful mutations induced by DNA lesions affect?


A: Potentially harmful mutations induced by DNA lesions can affect the survival of the cell's daughter cells after it divides.

Q: Why must the DNA repair process be constantly active?


A: The DNA repair process must be constantly active so it can respond rapidly to any damage in the DNA structure.

Q: What factors can affect the rate of DNA repair?


A: Many factors can affect the rate of DNA repair, including cell type, age of the cell, and the extracellular environment.

Q: What can happen to a cell that has accumulated a lot of DNA damage or one that no longer effectively repairs damage?


A: A cell that has accumulated a lot of DNA damage, or one that no longer effectively repairs damage, can enter one of three states.

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