What is a defensin?

Q: What is a defensin?


A: A defensin is a small cation protein found in animals and plants that serves as a host defence peptide.

Q: What pathogens do defensins combat?


A: Defensins work against bacteria, fungi, and many viruses.

Q: How many amino acids do defensins typically have?


A: Defensins have 18-45 amino acids.

Q: What is the purpose of cysteine residues in defensins?


A: Six to eight conserved cysteine residues are included in defensins.

Q: What types of cells in the immune system contain defensins?


A: Neutrophil granulocytes and almost all epithelial cells contain defensins to help kill phagocytosed bacteria.

Q: How do defensins kill bacteria?


A: Most defensins work by binding to the bacterial cell membrane and creating tiny holes in the membrane, causing vital ions and nutrients to leak out.

Q: Do only animal cells contain defensins?


A: No, both animal and plant cells contain defensins.

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