What is a molecular chaperone?
Q: What is a molecular chaperone?
A: A molecular chaperone is a protein that helps with protein folding.
Q: What is the main role of a molecular chaperone?
A: The main role of a molecular chaperone is protein folding.
Q: Do molecular chaperones occur in macromolecular structures during the structures' normal functions?
A: No, molecular chaperones do not occur in macromolecular structures during their normal functions.
Q: What are some of the things that molecular chaperones do to proteins?
A: Molecular chaperones can fold over half of all mammalian proteins, unfold proteins, assemble proteins, and disassemble proteins.
Q: What was the first protein to be called a chaperone, and what did it do?
A: The first protein to be called a chaperone assists the assembly of nucleosomes from folded histones and DNA.
Q: What is one major function of chaperones?
A: One major function of chaperones is to prevent polypeptide chains and subunits from sticking together in clumps which do not function.
Q: What is the difference between "holdases" and "foldases"?
A: "Holdases" act to stop aggregation, while "foldases" help fold proteins which cannot do it themselves.
