Saint Louis County (abbreviated St. Louis County) is a county located in the U.S. state of Minnesota. As of the 2010 census, the population was 200,226. Its county seat is Duluth. It is the largest county by total area in Minnesota. It is largest in the United States east of the Mississippi River.
Saint Louis County is included in the Duluth, MN-WI Metropolitan statistical area. Major industries include pulpwood production and tourism. Surface mining of high-grade iron-ore remains an important part of the economy of the Iron Range. Parts of the Bois Forte and Fond du Lac Indian reservations are in the county.