Roger David Kornberg (born (1947-04-24)April 24, 1947) is an American biochemist and Nobel prize winner. Kornberg got the Nobel Prize in Chemistry in 2006 for studying eukaryote transcription (the copying of information from DNA to RNA).

Kornberg is a professor of Structural Biology at Stanford University School of Medicine. His father, Arthur Kornberg, was also a professor at Stanford University, and got the Nobel Prize in Physiology or Medicine in 1959.